Yonus et al. Structure of the adenylation domain DltA 1 CRYSTAL STRUCTURE OF DLTA: IMPLICATIONS FOR THE REACTION MECHANISM OF NON-RIBOSOMAL PEPTIDE SYNTHETASE (NRPS) ADENYLATION DOMAINS*
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چکیده
Structure of the adenylation domain DltA 1 CRYSTAL STRUCTURE OF DLTA: IMPLICATIONS FOR THE REACTION MECHANISM OF NON-RIBOSOMAL PEPTIDE SYNTHETASE (NRPS) ADENYLATION DOMAINS* Huma Yonus, Piotr Neumann, Stephan Zimmermann, Jürgen J. May, Mohamed A. Marahiel and Milton T. Stubbs From the Institut für Biochemie und Biotechnologie, Martin-Luther-Universität HalleWittenberg, Kurt-Mothes-Straße 3, D-06120 Halle/Saale, Germany From the Fachbereich Chemie/Biochemie, Philipps-Universität Marburg, Hans-Meerwein Straße, D-35032 Marburg, Germany On leave from the Wydział Chemii, Uniwersytet Mikołaja Kopernika, Gagarina 7, 87-100 Torun, Poland From the Mitteldeutsches Zentrum für Struktur und Dynamik der Proteine, Martin-LutherUniversität Halle-Wittenberg Running head: Structure of the adenylation domain DltA Address correspondence to: Milton T. Stubbs, Institut für Biochemie und Biotechnologie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Straße 3, D-06120 Halle/Saale, Germany. Tel: +49 345 55 24901; Fax: +49 345 55 27013; E-mail: [email protected]
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Thiolation-enhanced substrate recognition by D-alanyl carrier protein ligase DltA from Bacillus cereus
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